Figure 1. SIVmac251 is susceptible to DRV and MRV.

Comparison between effective drug concentrations required for 50% and 90% inhibition of viral replication in vitro (respectively, EC₅₀ and EC₉₀) and the in vivo total levels (i.e. free and protein bound) of DRV and MRV in the plasma of six animals treated with H-iART. All values are displayed as mean + SEM.