Table 1:
Baseline characteristics of the different patterns of LGE in 63 patients who underwent aortic vale replacement
| No LGE | Mid-wall LGE | Infarct pattern LGE | P-value | |
|---|---|---|---|---|
| Number | 25 | 20 | 18 | |
| Age | 73 (60–77) | 71 (59–80) | 73 (67–77) | 0.83 |
| Male gender % | 60 | 80 | 89 | 0.080 |
| Comorbidity [n (%)] | ||||
| Coronary artery disease | 10 (40) | 9 (45) | 18 (100) | <0.001* |
| Hypertension | 13 (52) | 15 (75) | 11 (61) | 0.29 |
| Diabetes mellitus | 8 (32) | 6 (30) | 6 (33) | 0.985 |
| Hypercholesterolaemia | 13 (52) | 7 (35) | 10 (56) | 0.38 |
| Active smoking | 1 (4) | 3 (15) | 5 (29) | 0.10 |
| Chronic kidney disease ≥3 | 1 (4) | 4 (20) | 5 (28) | 0.081 |
| Previous CVA | 3 (12) | 0 (0) | 7 (39) | 0.003* |
| AF | 7 (28) | 3 (15) | 2 (11) | 0.37 |
| Left bundle branch block | 4 (16) | 0 (0) | 2 (11) | 0.20 |
| Right bundle branch block | 1 (4) | 2 (10) | 4 (22) | 0.21 |
| Medication [n (%)] | ||||
| ACEi/ARB | 13 (52) | 9 (45) | 10 (56) | 0.80 |
| Beta-blocker | 15 (60) | 7 (35) | 7 (39) | 0.19 |
| Statin | 15 (60) | 14 (70) | 16 (89) | 0.12 |
| Diuretic therapy | 11 (44) | 11 (55) | 8 (44) | 0.73 |
| CMR scan | ||||
| Indexed LV volume | 76 (67–100) | 91 (66–109) | 91 (78–113) | 0.22 |
| Indexed LV mass | 99 ± 27 | 113 ± 33 | 104 ± 25 | 0.26 |
| Ejection fraction | 64 ± 16 | 55 ± 20 | 52 ± 15 | 0.046* |
| Aortic valve area | 0.87 ± 0.30 | 0.95 ± 0.29 | 0.86 ± 0.19 | 0.55 |
| Bicuspid valve | 8 (32%) | 6 (30%) | 3 (17%) | 0.52 |
| % LGE mass | 0 (0–0) | 3.5 (1.9–4.6) | 5.8 (3.1–10.2) | <0.001* |
Parametric data presented as mean ± SD; non-parametric data as median (25th–75th IQR).
AF: atrial fibrillation; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blocker; CABG: coronary artery bypass graft operation; CVA: cerebrovascular accident; LGE: late gadolinium enhancement; LV: left ventricular.
*Denotes statistical significance (P < 0.05).