Table 2.

Comparison of the Gen-1 and Gen-2 hand-held optical probe (developed at the Optical Imaging Laboratory).

Gen-1 Hand-held probe	Gen-2 Hand-held probe
Segment 3-piece probe head design does not have good surface contact to curved surfaces.	A smooth contour to probe head design for maximum curved tissue surface contact
Not capable of collecting trans-illumination measurements towards improved depth recovery.	A forked probe head design with two probe heads that facilitates trans-illumination data acquisition
Aluminum-based probe heads is not patient comfortable upon tissue contact	A silicone-based probe head region(s) that directly contact the tissue surface
Large probe head area that introduced tension in the fibers upon flexing the probe to its curved position	A forked probe head design, with two probe heads of smaller surface areas
Bulky design to hold the probe during imaging studies	A smaller probe holder towards an actual hand-held size.