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(a) The relative level of AID mRNA in MEFs treated with 5-Aza-dC (1 μM). (b) The effect of AID down-regulation on mutagenic properties of 5-Aza-dC (c) The effect of PARP-1 inhibitor olaparib on mutagenic properties of 5-Aza-dC. (d) The effect of PARP-1 inhibitor olaparib on cytotoxic/cytostatic properties of 5-Aza-dC. Data shown as average ±SD; asterisk (*) designates statistically significant difference with corresponding control (* - p<0.05; ** - p<0.01; *** - p<0.001).
