Table 4.
Information at the time of detection of PR
| Clinicopathologic factors | Unresectable PR | Resectable PR | P |
|---|---|---|---|
| (n = 23) | (n = 13) | ||
| Interval between hepatectomy and PR, mo, median (range) | 6.0 (1.0–43.0) | 11.0 (1.0–102.0) | 0.009* |
| Interval between hepatectomy and peritoneal | |||
| Recurrence | |||
| ≤6 month | 13 (56.5%) | 5 (38.4%) | 0.080 |
| >6 month | 10 (43.4%) | 8 (61.5%) | |
| Tumor markers at PR | |||
| AFP level, mean ± SD | 16519.7 ± 45832.1 | 575.4 ± 1475.2 | 0.032* |
| AFT level | |||
| ≤200 ng/dl | 13 (56.5) | 10 (76.9) | 0.221 |
| >200 ng/dl | 10 (43.5) | 3 (23.1) | |
| PIVKA-II level | |||
| Mean ± SD | 407.0 ± 498.1 | 180.5 ± 348.8 | 0.034* |
| ≤200 mAU/ml | 11 (55.0) | 10 (83.3) | 0.102 |
| >200 mAU/ml | 9 (45.0) | 2 (16.7) | |
| No. of peritoneal lesions, median (range) | 2.0 (1.0–7.0) | 1.0 (1.0–4.0) | 0.044* |
| Single lesion | 6 (26.1%) | 7 (53.8%) | 0.096 |
| Multiple lesions | 17 (73.9%) | 6 (46.2%) | |
| Size of largest peritoneal lesion | |||
| Median (range), mm | 24.0 (4.0–60.0) | 35.0 (10.0–140.0) | 0.070 |
| ≤30 mm | 16 (69.6) | 7 (30.4) | 0.069 |
| >30 mm | 5 (38.5) | 8 (61.5) | |
| Total size of peritoneal lesion | |||
| Median (range), mm | 47.0 (20.0–255) | 60.0 (10.0–140.0) | 0.499 |
| ≤50 mm | 14 (60.9) | 9 (39.1) | 0.196 |
| >50 mm | 5 (38.5) | 8 (61.5) | |
| Location of PR | |||
| Omentum | 17 (73.9%) | 0 (0.0%) | <0.001* |
| Posterior peritoneum | 4 (17.4%) | 7 (53.8%) | |
| Anterior peritoneal/ abdominal wall | 2 (8.7%) | 2 (15.4%) | |
| Combination | 0 (0.0%) | 4 (30.8%) | |
| Posterior peritoneum with omental nodules | – | 3 (23.1%) | |
| Posterior peritoneum with chest wall | – | 1 (7.7%) | |
| Omental seeding | 17 (73.9%) | 3 (23.1%) | <0.003* |
| Other | 6 (26.1%) | 10 (76.9%) | |
* Statistically significant at P < 0.05