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. 2012 Apr 27;287(26):21584–21598. doi: 10.1074/jbc.M111.320481

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© 2012 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 4. — Progression of age-related hearing loss. ABR threshold to click stimuli was measured in aging Ceacam16^+/+ and Ceacam16^−/− mice, 1–19 months of age. Individual ear threshold (db SPL) was correlated to age (months). Continuous lines show a linear fit. Pearson product-moment correlation coefficient (R²) and significance of correlation is given close to the line fit. For both Ceacam16^+/+ and Ceacam16^−/− mice, loss of ABR hearing threshold showed a similar progression with age. Nevertheless, the threshold for Ceacam16^−/− mice was continuously significantly higher.