TABLE 1.

Apoptosis results of cells treated with GMX1778 repeated in triplicate were used for calculating average ± S.D. as in Fig. 5

GMX1778 concentrations used are in parentheses, and 20 μm NA was added concurrently with GMX1778.

Cell line	% apoptotic cells (annexin-V-positive)
	Control	GMX1778	GMX1778+ NA
U251 (5 nm)	11.9 ± 3.5	86.2 ± 5.3a	88.7 ± 2.6
HCT116 (5 nm)	12.8 ± 3.5	46.8 ± 6.3a	11.6 ± 2.4b
HCT116 p53−/− (5 nm)	11.7 ± 3.0	37.0 ± 4.5c	10.5 ± 2.9b
MDA-MB-231 BR (15 nm)	8.0 ± 4.8	93.8 ± 4.4a	90.8 ± 1.2
HMEC (50 nm)	10.0 ± 0.7	14.4 ± 2.5	10.8 ± 1.8
MCF10A (50 nm)	20.3 ± 7.8	17.1 ± 7.5	17.6 ± 4.2

^a p ≤ 0.001 compared with control.

^b p ≤ 0.001 compared with GMX1778 alone.

^c Increased cell death (p ≤ 0.05).