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. 2012 Jul;26(5):754–765. doi: 10.1016/j.bbi.2011.11.006

Fig. 4.

Fig. 4

Age related changes in CD11c and FcγRI expression depends on brain region. Tissue collected and analysed 24 h after intraperitoneal injection of saline or LPS. (A) CD11c expression in selected regions of the CNS. CD11c expression was significantly influenced by age, region and age × region (p < 0.001), but not LPS. n = 5 per region. (B) FcγRI expression in selected regions of the CNS. FcγRI expression was significantly influenced by region, age and LPS (p < 0.05). n = 4–5 mice per region. Horizontal bars denote a significant effect of age (4 m saline to 21 m saline) or LPS (21 m saline to 21 m LPS) within that region. Data is shown as mean ± SEM. ∗ denotes p < 0.05; ∗∗ denotes p < 0.01; ∗∗∗ denotes p < 0.001.