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. 2011 Nov 28;590(Pt 4):763–776. doi: 10.1113/jphysiol.2011.219907

Figure 5. Ca2+ dependence of GABAergic transmission is unaltered in Ophn-1-/y neurons.

Figure 5

A, mean evoked IPSC vs.{Ca2+}o fitted with a Hill equation: I =Imax{Ca2+}n/({Ca2+}n+Kd). Evoked IPSCs were smaller in Ophn-1−/y neurons, without alteration in the Hill coefficient (n) or Kd. B, percentage decrease in evoked IPSCs in Ophn-1−/y neurons remained constant at different {Ca2+}o levels relative to evoked IPSCs recorded from Ophn-1+/y neurons. C, representative evoked IPSCs recorded in the presence of different {Ca2+}o.