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. 2011 Dec 5;590(Pt 4):777–792. doi: 10.1113/jphysiol.2011.220236

Figure 5. Postnatal deletion of Pdk1 in pyramidal neurons does not induce deficits in synaptic plasticity.

Figure 5

A and B, synaptic plasticity is not perturbed in Pdk1−/− mice. The mean fEPSP slope versus time before and after induction of LTP (A) or LTD (B) in slices from WT and Pdk1−/− mice did not differ. Insets show representative fEPSP traces before and 180 min after induction of synaptic plasticity.