Table 1.
Voltage-gated calcium channel genes in vertebrates and Drosophila
Vertebrate gene nomenclature new/old* | Currents | Activation | Drosophila homolog/annotation number | Alternative name/allele | Drosophila references |
---|---|---|---|---|---|
Cav1.1/α1S Cav1.2/α1C Cav1.3/α1D Cav1.4/α1F | L-type | HVA** | DmCa1D/CG4894 | Ca-α1D | Zheng et al. 1995; Worrell & Levine, 2008 |
Cav2.1/α1A Cav2.2/α1B Cav2.3/α1E | P/Q-type N-type R-type | HVA | DmCa1A/CG43368 | cacophony (cac); nightblindA (nbA) | Smith et al. 1996; Peixoto et al. 1997{BK38} |
Cav3.1/α1G Cav3.2/α1H Cav3.3/α1I | T-type | LVA | DmαG/CG15899 | Ca1G; Dmα1G; Dmα1T; Ca-α1T | Gielow et al. 1995; Littleton & Ganetzky, 2000 |
Vertebrate calcium channel nomenclature is according to Dolphin (2009).
For Cav1 channels activation voltages of more hyperpolarized potentials have been reported (Chen et al. 2009; Striessnig et al. 2010; Bock et al. 2011).