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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Am J Med Genet A. 2012 Jun 7;158A(7):1620–1627. doi: 10.1002/ajmg.a.35418

Figure 4. Segregation of hindlimb enhancer variants in clubfoot family members.

Figure 4

Figure 4

A. Chromatogram shows the heterozygote C>T variant in HLEA in Family 1 (F1). This variant does not segregate with the nonsyndromic clubfoot phenotype. B. Chromatograms showing the C deletion in HLEB with both forward and reverse sequences. This polymorphism was present in three families (F2-4) and does not segregate with the nonsyndromic clubfoot phenotype. Het = heterozygote. WT = wild type, F = forward sequence, R = reverse sequence.