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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Adv Drug Deliv Rev. 2011 Aug 6;63(14-15):1282–1299. doi: 10.1016/j.addr.2011.07.001

Figure 6.

Figure 6

(A) Gd3+-DOTA functionalized CdSeTe/CdS QDs with glutathione (GSH) coating. (B) A NIR-fluorescence image [42] and T1 weighted MR image (bottom) of a mouse. A phantom containing 10 μM of Gd3+-DOTA-QDs was visualized by both fluorescence imaging and MRI. (C) QD with the biotinylated Gd-wedge, containing eight Gd-DTPA complexes with AnaxA5 (AnxA5-QD-Gd-wedge). This nanohybrid can be visualized by both fluorescence and MR imaging. (D) Schematic representation of a cNGR-labeled paramagnetic quantum dot. Commercially available this QD carries ~10 streptavidin moieties to which 6 cNGR groups and hence 24 gadolinium constructs were bound. Based on that estimation the maximum number of Gd3+ was 192 [102–104].