Fig. 1.

Morphologic changes and growth inhibition in FaDu cells following exposure to capsaicin. (A) As the incubation time increases, the cell density is reduced, reflecting the inhibitory effects of capsaicin on cell growth. Untreated FaDu cells at 12 h (a) and 24 h (b) and FaDu cells treated with 200 µM capsaicin for 12 h (c) and 24 h (d). (B) The cells were treated with various concentrations of capsaicin for 24, 48 and 72 h. Cell viability was determined by MTT assay. The IC₅₀ of capsaicin against FaDu cells was measured at around 150 µM. The vertical bars in (B) indicate the means and standard errors (n=3).