Fig. 6.

Fluoxetine enhanced the apoptosis ratio in ET-1induced human PASMCs. The result from Flow Cytometry are displayed for the ratio of apoptosis in the human PASMCs cultured with low-serum DMEM (2% FBS, Blank), ET-1, and fluoxetine with (ET-1+F) and without ET-1(F) for 72 h. Data are expressed as mean±SEM (n=6). ^*p<0.01 vs. Blank, ^†p<0.001 vs. ET-1. PASMCs, pulmonary artery smooth muscle cells; FBS, fetal bovine serum; ET-1, endothelin-1; DMEM, dulbecco's modified eagle medium; SEM, standard error of mean.