Table 2. Percent divergence of the nonstructural coding region of human PARV4–positive encephalitis patients VES065 and VES085, compared with previously described PARV4 variants*.
| Patient or genotype | Genotype 3, aa (nt), n = 1 | Genotype 2, aa (nt), n = 7 | Genotype 1, aa (nt), n = 11 | VES085 serum, aa (nt), n = 1 | VES085 CSF, aa (nt), n = 1 | VES065 CSF, aa (nt), n = 1 | |
|---|---|---|---|---|---|---|---|
| VES065 CSF, n = 1 | 9.5 (3.5) | 3.7 (1.5) | 10.3 (3.7) | 0.2 (0.0) | 0.2 (0.0) | ||
| VES085 CSF, n = 1 | 9.4 (3.5) | 3.6 (1.5) | 10.2 (3.7) | 0.0 (0.0) | |||
| VES085 serum, n = 1 | 9.4 (3.5) | 3.6 (1.5) | 10.2 (3.7) | ||||
| Genotype 1, n = 11 | 8.0 (2.6) | 9.3 (2.9) | 0.9 (0.6) | ||||
| Genotype 2, n = 7 | 8.6 (2.7) | 1.8 (0.7) | |||||
| Genotype 3, n = 1 | |||||||
*PARV4, human parvovirus 4; CSF, cerebrospinal fluid.