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. Author manuscript; available in PMC: 2012 Jun 25.
Published in final edited form as: J Am Coll Cardiol. 2009 May 5;53(18):1699–1707. doi: 10.1016/j.jacc.2009.01.056

Figure 3. Peri-infarct zone assessment by ex-vivo MRI (n=5).

Figure 3

(A) Long-axis orientation showing the extent of 1 and 8mm slice thickness for short axis images. The presence of both viable and non-viable tissues in the 8 mm slice results in partial volume averaging. (B) For the 8mm slice thickness, the septal infarct appears transmural (arrows) and the PIZ is less defined with a wide range of gray values. (C) In the 1mm short axis slice at the same region it can be appreciated that infarct is not transmural and has well-delineated borders (D, E) The same myocardial slices with computer –generated mask depicting the core infarct (red) and PIZ (yellow). The PIZ is larger at 8mm. (F) Ex-vivo and in-vivo MRI showed different assessment of the PIZ at 8mm and 4 mm *p< 0.01 and †p= 0.01, respectively)

The PIZ mass in ex-vivo MRI acquisitions as a function of slice thickness showed marked differences (‡p=0.004) and decreased with thinner slice thickness; 2mm versus 8mm §p= 0.01, and 1mm vs 4 and 8mm, p< 0.01 and #p< 0.001, respectively