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. 2012 Mar 21;4(5):658–667. doi: 10.1093/gbe/evs027

Table 3.

Power to Detect Adaptive Changes in Species with Different Effective Population Sizes

Nonsynonymous Sites
Adaptive Effectively Neutral Synonymous Sites α (%) ωa (%) MK Test P Value
Species A (large Ne)
    Polymorphisms n.a. 0 20
    Substitutions 15 0 100
100 15 0.024
Species B (low Ne)
    Polymorphisms n.a. 20 20
    Substitutions 15 100 100
13 15 0.685

Note.—Comparison between two hypothetical species (A and B) that have the same number of adaptive changes but different effective population sizes illustrated by a difference in the number of effectively neutral nonsynonymous sites. n.a., not applicable.