TABLE V.
Differences in TH2 cytokine levels between atopic and nonatopic subjects
| All atopy (n = 52) |
All without atopy (n = 16) |
P value |
STRA with atopy (n = 45) |
STRA without atopy (n = 8) |
P value |
Control with atopy (n = 7) |
Control without atopy (n = 8) |
P value |
|
|---|---|---|---|---|---|---|---|---|---|
| BAL fluid IL-4 (pg/mL) |
U (U-0.52) | U (U-0.5) | .74 | 0.23 (0-0.56) | U (U-0.39) | .37 | U | 0.3 (U-0.69) | .49 |
| BAL fluid IL-5 (pg/mL) |
U (U-1.39) | U | .49 | U (U-1.42) | U (U-1.1) | .79 | U | U | 1.0 |
| Biopsy specimen IL-5 (/mm2) |
55.7 (26.7-132.7) | 42.7 (31.7-75.2) | .70 | 51.8 (26.3-107.5) | 36.1 (28.3-49.3) | .40 | 206.2 (48.1-320.6) | 124.7* | * |
| BAL specimen IL-13 (pg/mL) |
U (U-4.58) | U | .58 | U (U-6.01) | U (U-16.7) | .97 | U | U (U-17.0) | 1.0 |
| Biopsy specimen IL-13 (/mm2) |
16.0 (7.5-39.1) | 12.2 (0-59.4) | .51 | 16.4 (11.7-33.7) | 12.2 (0-59.4) | .40 | 6.0 (2.1-102.3) | 19.8 (4.3-240.5) | .79 |
Values are presented as medians (IQRs).
U, Undetectable.
There were only 2 patients in this group and therefore a P value and IQR could not be calculated.