Table 3.
miRNAs that normalize after VAD support, n=10 VAD-supported hearts, 80% male, 40%, ischemic, average support time 1.7 months, type of device not disclosed. Fold change and p-values are listed for each miRNA. (Taken from Matkovich et al., 2009).
| Heart failure miRs that normalize after LVAD | ||||||
|---|---|---|---|---|---|---|
| Fold-change | P-value | |||||
| Name | Failing vs nonfailing |
Post-LVAD vs nonfailing |
Post-LVAD vs failing |
Failing vs nonfailing |
Post-LVAD vs nonfailing |
Post-LVAD vs failing |
| miR-27b | 3.15 | 1.14 | −4.75 | 2.60E-04 | 0.270 | 0.0620 |
| miR-30a-5p | 3.06 | 1.07 | −2.85 | 4.76E-04 | 0.566 | 0.0821 |
| miR-30c | 3.31 | 1.32 | −2.51 | 1.24E-04 | 0.105 | 0.0853 |
| miR-30d | 2.96 | 1.23 | −2.40 | 6.47E-04 | 0.211 | 0.116 |
| miR-103 | 3.54 | 1.20 | −2.94 | 1.24E-04 | 0.156 | 0.0834 |
| miR-130a | 3.06 | 1.36 | −2.26 | 6.80E-04 | 0.127 | 0.270 |
| miR-378 | 3.60 | 1.20 | −3.00 | 6.25E-05 | 0.153 | 0.0544 |
| let-7f | 4.84 | 1.18 | −4.11 | 1.50E-06 | 0.211 | 0.00543 |