Table 2.

Effect of acetazolamide on the pathological traits causing OSA

Trait	Baseline	Acetazolamide	P-value
Loop gain	3.4 [2.4–5.4]	2.0 [1.4–3.5]	<0.05
(l min−1)	3.5 [3.1–4.4]	4.8 [2.5–5.3]	0.15
Upper-airway gain	0.25 [–0.26–0.55]	0.27 [–0.27–0.58]	0.65
Arousal threshold (l min−1)	10.5 [10.1–11.8]	12.5 [9.8–15.5]	0.06

Data represent medians [interquartile ranges].