Figure 4. Effects of femoral arterial occlusion on ASIC3-like currents response to pH 6.7.
A, original traces of ASIC3-like current responsive to pH 6.7 recorded in DRG neurons innervating hindlimb muscles in control and after 24 h arterial occlusion. B, averaged data show mean current density of ASIC3-like currents activated by pH 6.7. Twenty-four hours of arterial occlusion induced a larger current density compared with control. *P < 0.05 vs. control. C, percentage of DRG neurons innervating muscle with ASIC3-like currents responsive to pH 6.7. A larger percentage of DRG neurons with ASIC3-like currents were observed in 24 h of arterial occlusion than in control. *P < 0.05 compared with control.