Table 2. ERG results for individual dogs comparing pre-treatment and 4 months post-treatment for first and second injected eyes.
| Dog | Eye |
Rod a-wave pre-injection (μV) |
Rod a-wave 4 months post-injection (μV) |
Rod b-wave pre-injection (μV) |
Rod b-wave 4 months post-injection (μV) |
Cone flicker pre-injection (μV) |
Cone flicker 4 months post-injection (μV) |
|---|---|---|---|---|---|---|---|
| 1 | First (a) | 0 | 2 | 0 | 7 | 0 | 4 |
| Second (b) | 0 | 4 | 0 | 21 | 0 | 4 | |
| 2 | First (a) | 0 | 28 | 0 | 94 | 0 | 9 |
| Second (b) | 0 | 1 | 0 | 3 | 0 | 0 | |
| 3 | First (a) | 0 | 4 | 0 | 20 | 0 | 5 |
| Second (b) | 0 | 3 | 0 | 15 | 0 | 2 | |
| 4 | First (a) | 0 | 0 | 0 | 0 | 0 | 0 |
| Second (b) | 0 | 4 | 0 | 9 | 0 | 3 | |
| 5 | First (a) | 0 | 5 | 0 | 16 | 2 | 8 |
| Second (b) | 0 | 19 | 0 | 45 | 0 | 7 | |
| 6 | First (a) | 0 | 22 | 0 | 56 | 0 | 4 |
| Second (b) | 0 | 44 | 0 | 111 | 0 | 14 | |
| 7 | First (a) | 0 | 10 | 0 | 24 | 0 | 3 |
| Second (b) | 0 | 11 | 0 | 21 | 0 | 3 | |
| 8 | First (a) | 0 | 8 | 0 | 18 | 0 | 4 |
| Second (b) | 0 | 5 | 0 | 18 | 0 | 2 | |
| 9 | First (a) | 0 | 50 | 0 | 107 | 0 | 15 |
| Second (b) | 0 | 24 | 0 | 43 | 0 | 5 | |
| Normalsa | 46 (±18) | 124 (±38) | 21 (±9) | ||||
Abbreviation: ERG, electroretinography.
a
ERG results from 18 RPE65+/+ eyes of dogs of similar breeding (mean±s.d.).
Rod responses recorded at 0.0 log cdSm−2, cone responses recorded from 33Hz flicker.