Table 4. Impact of variables affecting mean rod and cone rescue at 4 months (P-values displayed).
Variable (P-value) |
Rod b (0 log cdSm−2) |
Cone (33Hz) flicker |
---|---|---|
Age at injection | 0.438 | 0.229 |
Total dose of vector for both first and second injected eyes |
0.564 | 0.601 |
Total dose of vector—first injected eyes | 0.42 | 0.56 |
Total dose of vector—second injected eyes | 0.69 | 0.64 |
Volume of injection | 0.653 | 0.843 |
Concentration (vpml−1) | 0.511 | 0.565 |
Subretinal bleb size | 0.024* | 0.0034* |
Peak NAb response | 0.161 | 0.123 |
Change in NAb levels (before and after injection) | 0.146 | 0.102 |
NAb level at time of second injection with ERG outcome in second eye |
0.718 | 0.909 |
Abbreviations: ERG, electroretinography; NAb, neutralizing antibody.
Significant correlation.