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. Author manuscript; available in PMC: 2012 Jun 25.
Published in final edited form as: Gene Ther. 2010 Aug 12;18(1):53–61. doi: 10.1038/gt.2010.111

Table 4. Impact of variables affecting mean rod and cone rescue at 4 months (P-values displayed).

Variable (P-value) Rod b (0 log
cdSm−2)
Cone (33Hz)
flicker
Age at injection 0.438 0.229
Total dose of vector for both first and second
injected eyes
0.564 0.601
Total dose of vector—first injected eyes 0.42 0.56
Total dose of vector—second injected eyes 0.69 0.64
Volume of injection 0.653 0.843
Concentration (vpml−1) 0.511 0.565
Subretinal bleb size 0.024* 0.0034*
Peak NAb response 0.161 0.123
Change in NAb levels (before and after injection) 0.146 0.102
NAb level at time of second injection with ERG
outcome in second eye
0.718 0.909

Abbreviations: ERG, electroretinography; NAb, neutralizing antibody.

*

Significant correlation.