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. Author manuscript; available in PMC: 2013 Jan 1.
Published in final edited form as: J Immunol. 2012 Jun 4;189(1):102–111. doi: 10.4049/jimmunol.1200282

Figure 4. Impaired humoral immune response in the Spns2tm1a/tm1a mouse line.

Figure 4

Wild type (+/+) and Spns2tm1a/tm1a (tm1a/tm1a) mice were immunized intra-nasally with TetC, boosted at days 7 and 21, and analyzed for antigen specific antibody titers in the serum at day 36. Bars represent means ± SEM; *p<0.05, ** p<0.01, ns- non-significant, using Student’s t-test; data from 6 mice per group.