Table 1.
The information on the human brain tissues used in the experiments
| Case | Gender | Age (yr) | PMI (h) | Braak stage | Neuritic plaques – Temporal pole | Neuritic plaques – Hippocampus |
|---|---|---|---|---|---|---|
| AD1 | M | 86 | 4.4 | VI/VI | 25–30 per 100 × microscope field | Rare |
| AD2 | F | 89 | 3.3 | VI/VI | 10–15 per 100× microscope field | Rare |
| AD3 | F | 89 | 13.6 | VI/VI | 10–20 per 100× microscope field | Occasional |
| AD4 | F | 81 | 2.5 | VI/VI | Up to 30 per 100 × microscope field | Many |
| AD5 | F | 89 | 5.5 | VI/VI | Up to 30 per 100× microscope field | Many |
| AD6 | F | 89 | 13.8 | VI/VI | Up to 10 per 100× microscope field | Up to 6 per 100× microscope field |
| AD7 | F | 83 | NA | V/V | Severe | Up to 20 per 100× microscope field |
| AD8 | M | 75 | 8.3 | III/III | Severe | Up to 20 per 100× microscope field |
| AD9 | M | 72 | 2.3 | VI/VI | Severe | Up to 20 per 100× microscope field |
| AD10 | F | 89 | 3.5 | VI/VI | Many | Up to 20 per 100× microscope field |
| AD11 | F | 89 | 6.7 | VI/VI | Up to 25 per 100× microscope field | Present |
| AD12 | F | 89 | 4.2 | VI/VI | Up to 30 per 100× microscope field | Up to 15 per 100× microscope field |
| Mean ± SE | 9F/3M | 85 ± 1.75 | 6.19 ± 1.24 | |||
| ND1 | M | 89 | 4.9 | II/II | Very rare | Very rare |
| ND2 | M | 74 | 4.3 | II/0 | Absent | Absent |
| ND3 | F | 67 | 5 | 0 | Absent | Absent |
| ND4 | M | 62 | 4.3 | 0 | Absent | Absent |
| ND5 | M | 87 | 5.2 | III/I | Absent | Absent |
| ND6 | F | 76 | 3.6 | 0/I | Absent | Absent |
| ND7 | M | 89 | 3 | I/I | Absent | Absent |
| NAD8 | F | 74 | 18.7 | II/0 | Absent | Absent |
| Mean ± SE | 3F/5M | 77.25 ± 3.61 | 6.13 ± 1.81 |
AD, Alzheimer's disease; ND, non-Alzheimer disease; F, female; M, male; PMI, postmortem interval; SE, standard error.