Table 1.
Etiology and Clinical Characteristics of 1,147 Cases of ALF
| Feature | Acetaminophen (n = 532) |
Drugs (n = 133) |
Indeterminate (n = 161) |
Hepatitis A (n = 31) |
Hepatitis B (n = 83) |
All Others (n = 207) |
|---|---|---|---|---|---|---|
| Age (years)* | 37 (28–45) | 46 (33–56) | 38 (26–50) | 47 (40–57) | 42 (29–54) | 42 (29–56) |
| Female Sex | 76% | 67% | 58% | 45% | 42% | 76% |
| Jaundice to Coma (days)* | 0 (0–1) | 9 (3–20) | 9 (2–20) | 3 (1–8) | 7 (2–14) | 7 (1–17) |
| Coma grade ≥ 3 | 52% | 38% | 50% | 55% | 54% | 41% |
| ALT (U/L)* | 4067 (2138–6731) | 600 (260–1537) | 847 (396–2111) | 2404 (1367–3333) | 1707 (745–2815) | 650 (172–1867) |
| Bilirubin (mg/dL)* | 4.5 (2.9–6.6) | 20.2 (12.1–28.3) | 23.0 (9.2–29.7) | 11.9 (9.7–27.5) | 19.7 (12.4–25.6) | 15.3 (6.3–26.7) |
| Spontaneous Survival | 65% | 29% | 25% | 58% | 25% | 34% |
| Transplantation | 9% | 41% | 43% | 29% | 47% | 33% |
| Death Without Transplantation | 26% | 31% | 32% | 13% | 28% | 33% |