Table 2.
Comparison of the means ± SEM of the basal protein expression of Homer1b/c, Homer2a/b, mGluR1, mGluR5, NR2A, NR2B, PI3K, and p-(Tyr)p85α PI3K binding motif [p-PI3K] within the NAC core in the 15th generation offspring of mice selectively bred for a high DID drinking phenotype (HID-1; n=14), compared with the HS/Npt founder population (HS/Npt; n=14). The data are expressed as a percent of the mean optical density values of HS/Npt animals.
HS/Npt | HDID-1 | |
---|---|---|
Homer1b/c | 100±8.67 | 106.88±9.42 |
Homer2a/b | 100±14.22 | 82.03±12.53 |
mGluR1 | 100±16.05 | 151.12±20.72 |
mGluR5 | 100±8.52 | 96.76±12.66 |
NR2A | 100±17.13 | 109.43±16.17 |
NR2B | 100±7.32 | 98.39±8.86 |
PI3K | 100±15.51 | 106.82±20.0 |
p-PI3K | 100±17.30 | 100.81±15.15 |
binding motif |