Table 1.
Characteristics of the cells used in the study.
| Cell Name | Origin | p53 status | p73 status | Reference |
|---|---|---|---|---|
| MDAH041 (041) | Li-Fraumeni Syndrome | Negative | Endogenous | Bischoff et al 1991 |
| 041-p53 (C11) | 041 | Wild-type | Endogenous | Agarwal et al 1998a |
| 041-ddp73 (C17) | 041 | Negative | Inactive by dominant negative | Amin et al 2007a |
| shBim, #1 | 041 | Negative | Endogenous | Amin et al 2010a |
| shBim, #8 | 041 | Negative | Endogenous | New |
| shBim, #10 | 041 | Negative | Endogenous | Amin et al 2010a |
| SKOV3 | Ovarian cancer | Negative | Endogenous | Agarwal et al 2006 |
| SK-p53 | SKOV3 | Wild-type | Endogenous | Agarwal et al 2006 |
| SKOV3-ddp73, #C3 | SKOV3 | Negative | Inactive (dominant negative) | New |
| SKOV3-ddp73, #C5 | SKOV3 | Negative | Inactive by dominant negative | New |
| SKOV3-shNoxa, #6 | SKOV3 | Negative | Endogenous | New |
| SKOV3-shNoxa, #9 | SKOV3 | Negative | Endogenous | New |
| SKOV3-shBim, #6 | SKOV3 | Negative | Endogenous | Amin et al 2010a |
| PC3 | Prostate cancer | Negative | Endogenous | Hastak et al 2005 |
| PC3-p53 | PC3 | Wild-type | Endogenous | Hastak et al 2005 |
| A549 | Lung cancer | Wild-type | Endogenous | Amin et al 2010b |
| PCI-13 | Head and Neck cancer | Mutant | Endogenous | Heo et al 1989 |
| Tu686 | Head and Neck cancer | Mutant | Endogenous | Amin et al 2010b |