Table 2.
Mean (±SEM) latency (sec) to lever-press in both ethanol- and sucrose-reinforced groups following either aCSF or TTX microinjection.
Data are collapsed over the Seeking and Intake experiments (i.e., experiments with the same training protocol and response requirements) and represent only animals that responded following both microinjections (indicated in parentheses after the group name; number of subjects responding as a function of total number in that group). Open circles denote marginal effect of TTX relative to aCSF, within the ethanol groups only (p<.08).
| Seeking Experiments | Intake Experiments | ||||
|---|---|---|---|---|---|
| aCSF | TTX | aCSF | TTX | ||
|
|
|
||||
| EtOH (9/17) | 122.1 (54.8) | 303.9 (124.2)○ | EtOH (9/14) | 46.0 (15.1) | 166.7 (71.3)○ |
| SUC (15/16) | 51.9 (12.8) | 190.7 (83.2) | SUC (13/17) | 111.6 (63.7) | 101.7 (44.6) |