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. Author manuscript; available in PMC: 2012 Oct 1.
Published in final edited form as: Gene Ther. 2011 Jul 21;19(4):385–391. doi: 10.1038/gt.2011.108

Figure 1.

Figure 1

Survival of Mut-/- mice after rAAV9-CBA-mMut gene therapy treatment. Survival is shown in days between untreated Mut-/- mice (n=58) and Mut-/- mice treated with a single intrahepatic dose of 1×1010 GC of rAAV9-CBA-mMut (n=11)., 82% (n=9) of treated Mut-/- mice were alive at day of life (DOL) 365. All untreated Mut-/- mice perished by DOL 72, with the majority of deaths occurring before DOL 24. *** rAAV9-CBA-mMut treated Mut-/- mice survive significantly longer than untreated Mut-/- mice (p<0.001).