Table 5.
| Study and Authors | Sample Characteristics APS(Attenuated Psychotic Symptoms) BLIPS(Brief Limited Psychotic Symptoms) Trait (Genetic risk) |
Duration and Instruments |
Rates of Conversion to Psychosis |
|---|---|---|---|
| Personal Assessment and Crisis Evaluation Clinic (PACE) Nelson et al., 2011 |
Sample size=817 Help- seeking 83 percent with APS 27 percent with Trait |
6 months Comprehensive Assessment for At Risk Mental State (CAARMS) |
72/817 = 9 percent APS alone=9.4 percent APS + Trait = 8.7 percent |
| North America Prodrome Longitudinal Study (NAPLS) Cannon et al., 2008 |
Sample size=291 Help- seeking 97 percent with APS |
30 months Structured Interview for Prodromal Symptoms (SIPS) |
82/291 = 28 percent Conversion rate increased to 52 percent among 118 individuals with APS+Genetic Risk |
| Outreach and Support in South London (OASIS) Fusar-Poli et al., 2010 |
Sample size=152 Help- seeking Ultra-High Risk (all three groups) |
24 months CAARMS |
24/152 = 15.6 percent |
| European Prediction of Psychosis Study (EPOS) Ruhrmann et al., 2010 |
Sample size=245 Help-seeking Ultra-High Risk (all 3 groups) and Basic- Symptom based COGDIS |
18 months SIPS and Bonn Scalefor the Assessment of Basic Symptoms (BSABS) |
37/183 = 20 percent By UHR criteria 21 percent By COGDIS criteria 19 percent |
| Edinburgh High-Risk Study (EHRS) Johnstone et al., 2005 |
Sample size = 163 Young adults with family history of schizophrenia (two affected relatives) |
30 months | 20/147 = 13 percent Presence of schizotypy increased likelihood of conversion |
| UCLA Study Schlosser et al., 2011 |
Sample size=84 Help- seeking Ultra-High Risk |
24 months SIPS |
27/84 = 32 percent |
| Orygen Youth Health (OHY) Yung et al., 20008 |
Sample size=119 Help- seeking Ultra-High Risk |
24 months CAARMS |
19/119 = 16 percent |