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Norepinephrine (NE) increases Nox1 expression. A) Isolated fetal hearts (FH) or H9c2 cells were treated with 10 μM NE for 48 h. B) H9c2 cells were transfected with two sets of different sequences of siRNA (Si-1 and Si-2) against Nox1 or Nox4, respectively. Protein and mRNA abundance of Nox1 and Nox4 was determined. Data are means ± se, n = 6. *P < 0.05 vs. control.
