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. 2012 Jul;26(7):2986–2999. doi: 10.1096/fj.12-204495

Figure 4.

Figure 4.

Protein expression of 19S and 20S proteasome subunits in control (con) and denervated (den) muscle. A, B) Western blots of lysates from the TS of WT (n=3–4) and MuRF1-KO (n=4) mice following 3 and 14 d of denervation. Immunoblots for PSMA6 (α1, 20S subunit; A, top panel) and Ponceau staining (A, bottom panel) and PSMC2 (Rpt1, 19S subunit; B, top panel) and Ponceau staining (B, bottom panel). C–F) Quantification of immunoblots from WT (solid bars) and MuRF1-KO (open bars) mice; data are expressed as means ± sd. Relative amounts (expressed as a percentage of WT con) of PSMA6 protein (C, E) or PSMC2 protein (D, F) in TS after 3 d (C, D) or 14 d (E, F) of denervation. *P < 0.05, **P < 0.001.