Table 2.

Effect of each inhibitor administered alone on LVP

Inhibitor	Biological activity	LVP (Δ%)
Nebivolol (100 nM)	Selective β1-AR antagonist	0.53 ± 0.46
CGP20712A (100 nM)	More selective β1-AR antagonist	−2.41 ± 1.12
MDL 12330A (100 nM)	Selective AC inhibitor	−3.1 ± 2.6
KT5720 (100 nM)	Selective PKA inhibitor	−5.9 ± 3.7
Milrinone (0.1 μM)	Selective PDE3 inhibitor	3.1 ± 2.1
Thapsigargin (100 nM)	Selective SERCA2a inhibitor	4.7 ± 2.8