Table 1. Measurements of blood components sampled at time points during blood and N. meningitidis co-cultivation.
| Blood donor | Addition of bacteria | Bactericidal activity1 | Time point | Glucose (mmol/l) | Lactate (mmol/l) | C3 (g/l) | CH50 (U/ml) |
| A | No | n/a | 0 | 4.6 | 2.7 | 1.00 | nd |
| A | No | n/a | 90 | 3.7 | 4.9 | 0.99 | 34 |
| A | No | n/a | 240 | 1.9 | 8.8 | 1.05 | 33 |
| A | Yes | Non-killer | 90 | 3.4 | 4.9 | 1.00 | 30 |
| A | Yes | Non-killer | 240 | 1.2 | 7.9 | 1.06 | 26 |
| A+C2 | Yes | Killer | 90 | 3.6 | 4.6 | 1.01 | 32 |
| A+C2 | Yes | Killer | 240 | 1.8 | 8.9 | 1.07 | 30 |
| C | No | n/a | 0 | 5.3 | 1.6 | 1.08 | 41 |
| C | No | n/a | 90 | 3.8 | 4.5 | 1.08 | nd |
| C | No | n/a | 240 | 2.0 | 8.7 | 1.07 | nd |
| C | Yes | Killer | 90 | 3.5 | 3.9 | 1.08 | 42 |
| C | Yes | killer | 240 | 0.8 | 2.8 | 1.11 | 36 |
| Normal range | 3.0–5.5 | 0.5–2.2 | 0.7–1.7 | 23–46 | |||
1
Bactericidal activities are defined by reduction of CFU, shown in Figure 1A and C.
2
A+C: Blood from donor A with addition of plasma from donor C to 10%.
n/a: not applicable; nd: not determined.