Table 3. Differentially expressed meningococcal genes encoding virulence factors^* during blood co-cultivation compared with T = 0min samples (log₂ ratio, p<0.01 with FDR).

Gene number	Gene name	Function	Co-cultivation time points
			20min	40min	60min	90min	240min
NMB0014	kdtA	Octulosonic-acid transferase					0.851
NMB0018	pilE	Major pilin	0.837	0.714	0.723
NMB0051	pilU	Twitching motility protein	0.618	0.603			−0.602
NMB0179	fabZ	3R-hydroxymyristoyl-ACP dehydratase			0.596		0.614
NMB0199	lpxB	Lipid-A-disaccharide synthase				0.691	0.657
NMB0216	katA	Catalase		2.656	2.750	3.301	2.483
NMB0393		Multidrug resistance protein				0.816
NMB0586		Putative adhesin		0.649
NMB0922	lst	Alpha-2,3-sialyltransferase	1.159	0.809	0.913		0.686
NMB0926		Opacity protein		0.673			−0.884
NMB0995	mip	Macrophage infectivity potentiator	1.337	0.958	0.741	0.734	0.729
NMB1053	opcA	Class 5 outer membrane protein	1.124	1.068
NMB1206	bfrB	Bacterioferritin B	2.482	1.193	0.633		1.001
NMB1207	bfrA	Bacterioferritin A	2.186	0.969			1.164
NMB1332	prc	Carboxy-terminal peptidase					1.217
NMB1704	lgtF	Beta-1,4-glucosyltransferase	0.960	0.844	0.884	0.760	0.806
NMB1705	rfaK	Acetylglucosamine transferase		0.654			1.041
NMB1779		hemagglutinin/hemolysin					1.057
NMB1880	fetB2	Putative ABC transporter, periplasmic solute-binding protein					1.233
NMB1882		TonB-dependent receptor				0.866
NMB1926	lgtE	Lacto-N-neotetraose biosynthesis glycosyl transferase					0.725
NMB1928	lgtB	Lacto-N-neotetraose biosynthesis glycosyl transferase					0.600
NMB1929	lgtA	Lacto-N-neotetraose biosynthesis glycosyl transferase	0.726		0.904	0.779	0.974
NMB1961		VacJ-related protein	0.742	0.691	0.721	0.634
NMB2132		Transferrin binding protein-related	0.661

^*as listed by Tettelin et al. [6].