Figure 6. SDF-1 stimulates proliferation of epithelial cells in ICCs from early gestational human fetal pancreas.

ICCs isolated from fetal pancreas of 12 to 14 weeks were grown in suspension culture, treated with 10% human serum alone, with HGF (10 ng/ml) or with SDF-1α (100 ng/ml) for six days. ICCs were fixed and analyzed by immunofluorescence staining. PanCytokeratin (green) is an epithelial marker. Ki67 (red) is used as a marker of proliferation.