Table 1. Comparison of mRNA expression levels of genes encoding for transporter proteins and junctional proteins in PCP-R and porcine CP tissue.
gene | Porcine CP tissue | PCP-R |
Claudin-1 | 100±15.7 | 39.3±7.4** |
Claudin-3 | 100±12.5 | 5.8±3.7*** |
ZO-1 | 100±31.6 | 20.5±12.3* |
Occludin | 100±13.9 | 34.9±10.1** |
E-cadherin | 100±4.8 | 3351.8±1464.5 |
DMT-1 | 100±18.4 | 2.4±0.8* |
TFRC | 100±27.2 | 73.8±74.9 |
ZnT1 | 100±27.1 | 5.7±4.1* |
ATP7A | 100±22.7 | 4.3±1.8* |
The mRNA expression of all analyzed genes was normalized that of β-actin in the same sample. The expression in porcine CP tissue was arbitrarily set as 100%. Data represent mean ± SD (n = 3).
p<0.05.
p<0.01.
p<0.001 as compared to controls.