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. 2012 Jun 22;7(6):e39155. doi: 10.1371/journal.pone.0039155

Figure 1. Persistence of P. acnes in livers of WT and TLR9−/− mice.

Figure 1

Groups of five WT and TLR9−/− mice were treated with heat-killed P. acnes (100 µg/g b.w.) i.v. and livers were removed at different time points after treatment. Immunohisto-chemical staining of liver sections using P. acnes specific antiserum shows brown P. acnes-specific staining within granulocytes, sinusoidal lining cells and/or granulomas. Left panel: liver of WT mice; right panel: liver of TLR9−/− mice. One representative slide per group of five animals is shown.