Table 1. Assessment of brain injury.
| Group | UVC (n = 6) | Prot VT (n = 5) | High VT (n = 5) | ||||||
| Incidence and severity of injury (%) | Incidence | Mild | Severe | Incidence | Mild | Severe | Incidence | Mild | Severe |
| Gross Anatomical Injury | |||||||||
| Periventricular white matter | 0 | 0 | 0 | 40 | 20 | 20 | 20 | 20 | 0 |
| Subcortical white matter | 12 | 0 | 12 | 40 | 40 | 40 | 40 | 20 | 20 |
| Lipid Peroxidation | |||||||||
| Periventricular white matter (cells/mm2) | 245±99 | 412±41 | 580±60*# | ||||||
| Subcortical white matter (cells/mm2) | 271±73 | 393±38 | 402±39 | ||||||
| Vascular protein extravasation | |||||||||
| Periventricular & subcortical white matter (%) | 0 | 0 | 60*# | ||||||
| Infiltrating inflammatory cells | |||||||||
| Periventricular white matter (cells/mm2) | 120±37 | 205±26 | 211±65 | ||||||
| Subcortical white matter (cells/mm2) | 196±58 | 536±40 | 728±242* | ||||||
Incidence and severity of gross anatomical brain injury expressed as % of the lambs displaying evidence of mild or severe injury. *indicates significant difference between High VT and UVC. #indicates significant difference between High VT and Prot VT.