Figure 6. Effects of linagliptin on liver Suppressor of cytokine signaling 3 (SOCS3) protein expression.

SOCS3 protein staining of liver specimens from diet-induced obesity (DIO) mice treated with vehicle, linagliptin 3 mg/kg/day (B), linagliptin 30 mg/kg/day (C) and chow-fed mice (D). Quantification of staining was performed by histologic scoring (n = 9 animals per group). Data are shown as mean ± SEM. *P<0.05.