Fig. 2.

Representative regular bright-field images of H&E stained epithelial cell nuclei and corresponding structure-derived nuclear optical path length (OPL) maps for three selected cells derived from (a) wild-type mouse (six weeks), (b) histologically normal appearing cells (uninvolved cells) from six weeks ${\mathit{Apc}}^{\mathrm{Min}}$ mouse, and (c) histologically normal appearing cells (uninvolved cells) from 4.5 months ${\mathit{Apc}}^{\mathrm{Min}}$ mouse. The marked area in part (a) shows the representative columnar shaped epithelial cells having similar morphological features.