| High: | ⊕⊕⊕⊕ | Further research is very unlikely to change our confidence in the estimate of effect. |
| Moderate: | ⊕⊕⊕⃝ | Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. |
| Low: | ⊕⊕⃝⃝ | Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. |
| Very low: | ⊕⃝⃝⃝ | Any estimate of effect is very uncertain. |
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