Table 17: Summary of Findings on Diabetes Resolution After Roux-en-Y Gastric Bypass.
Study (Year) |
Diabetes Definition | Follow-p, Months | Patients With Comorbidity at Baseline, N | Resolved, % (n) | Improved, % (n) | No Change, % (n) | Worse, % (n) |
---|---|---|---|---|---|---|---|
Wittgrove (2000) | Diabetes mellitus, no further definition | 3–60 | 85 | 99 (84) | 1 (1) | 0 (0) | 0 (0) |
Cowan (1998) | Fasting blood glucose > 140 mg/dl or 7.77 mmol/l | 6–12 | 13 | 92 (12) | 8 (1) | 0 (0) | 0 (0) |
Smith (1996) | Study did not categorize patients as having or not having diabetes, but instead determined if patients were taking insulin, oral hypoglycemics, a controlled diet, or no treatment. ECRI classed the first 3 as indicating diabetes and the last category as not indicating diabetes. | 3–84 | 118 | 74 (87) | Not reported | Not reported | Not reported |
Pories (1995) |
Non insulin dependent diabetes, abnormal values of blood glucose and glycosylated hemoglobin | < 12–168, (mean, 108) | 165 | 83 (121/146) |
Not reported | Not reported | Not reported |
(Table reproduced with kind permission from ECRI. Bariatric Surgery for Obesity. 2004. Plymouth Meeting, PA, ECRI. Technology Assessment Report.)