Adverse Effects After Roux-en-Y Gastric Bypass. From ECRI (19).
| Study (Year) | Timing of Event | Description | Patients, % (n/N) |
|---|---|---|---|
| Smith (2004) | Perioperative | Mortality | 0.1% (1/779)* |
| Any | Mortality | 0.1% (1/779) | |
| Gastrojejunal perforation | 1.2% (9/779) | ||
| Gastrojejunal stenosis | 7.6% (59/779) | ||
| Ventral incisional hernia | 5.8% (45/779) | ||
| Cholecystitis | 1.3% (10/779) | ||
| Gastrointestinal hemorrhage | 2.8% (22/779) | ||
| Abdominal wall hematoma | 0.6% (5/779) | ||
| Wound infection | 4.1% (32/779) | ||
| Deep vein thrombosis | 0.5% (4/779) | ||
| Pulmonary embolus | 0.5% (4/779) | ||
| Dehydration | 6.4% (50/779) | ||
| Myocardial infarction | 0.1% (1/779) | ||
| Small bowel obstruction | 4.4% (34/779) | ||
| Voice change post-intubation | 0.1% (1/779) | ||
| Gastrojejunal ulcer – no bleeding | 0.3% (2/779) | ||
| Splenectomy | 0.3% (2/779) | ||
| Appendicitis | 0.5% (4/779) | ||
| Subphrenic abscess without perforation | 0.3% (2/779) | ||
| Pneumonia | 1.2% (9/779) | ||
| Jejunojejunostomy perforation | 0.1% (1/779) | ||
| Superior mesenteric vein thrombosis | 0.1% (1/779) | ||
| Guillain barre syndrome | 0.1% (1/779) | ||
| Suicide | 0.1% (1/779) | ||
| Gilbert’s disease | 0.1% (1/779) | ||
| Nephrolithiasis | 0.9% (7/779) | ||
| Pseudomembranous colitis | 0.8% (6/779) | ||
| Decubitus ulcer | 0.3% (2/79) | ||
| Pelvic inflammatory disease | 0.1% (1/779) | ||
| Diverticulitis | 0.1% (1/779) | ||
| Dehiscence/evisceration | 0.1% (1/779) | ||
| Severe colonic inertia | 0.1% (1/779) | ||
| Clinical dumping syndrome | 0.1% (1/779) | ||
| Stroke cerebral aneurysm | 0.1% (1/779) | ||
| Beriberi | 0.1% (1/779) | ||
| Arrhythmia | 0.4% (3/779) | ||
| Heparin induced thrombocytopenia | 0.1% (1/779) | ||
| Any | 32.2% (251/779) | ||
| Perugini (2003) | Perioperative | Conversion to open surgery | 1.1% (2/188) |
| Any | Gastrojejunal leak | 1.6% (3/188) | |
| Mortality | 1.1% (2/188) | ||
| Stenosis at gastrojejunal anastomosis | 14.4% (27/188) | ||
| Staple line hemorrhage | 3.2% (6/188) | ||
| Bowel obstruction | 3.2% (6/188) | ||
| Roux limb obstruction at jejunostomy | 1.6% (3/188) | ||
| Nausea | 1.1% (2/188) | ||
| Infected hematoma | 1.1% (2/188) | ||
| Wound infection | 0.5% (1/188) | ||
| Left upper quadrant pain, unspecified | 0.5% (1/188) | ||
| Upper gastrointestinal hemorrhage | 2.1% (4/188) | ||
| Gastric perforation | 0.5% (1/188) | ||
| Incarcerated hernia | 0.5% (1/188) | ||
| Gastric outlet obstruction/bezoar | 0.5% (1/188) | ||
| Gastrogastric fistula | 0.5% (1/188) | ||
| Bile leak | 0.5% (1/188) | ||
| OR bleeding splenectomy | 0.5% (1/188) | ||
| Wittgrove (2000) |
Perioperative | Mortality | 0% (0/500) |
| Any | Stenosis | 1.6% (8/500) | |
| Hemorrhage requiring reoperation | 0.8%(4/500) | ||
| Mortality | 0% (0/500) | ||
| Major infection | 0.8% (4/500) | ||
| Minor infection | 4.8% (24/500) | ||
| Small bowel obstruction | 0.6% (3/500) | ||
| Reoperation due to leak | 2.2% (11/500) | ||
| Leak | 2.2% (11/500) | ||
| Pyelonephritis | 0.2% (1/500) | ||
| Respiratory | 1.4% (7/500) | ||
| Stroke | 0.2% (1/500) | ||
| Incisional hernia | 0% (0/500) | ||
| Spaulding (1997) |
Late | Marginal ulcer | 9.3% (14/150) |
| Stomal stenosis | 24% (36/150) | ||
| Smith (1996) | Early | Mortality | 0.5% (1/205) |
| Late | Major complications | 6.8% (14/205) | |
| Major hemorrhage | 2.4% (5/205) | ||
| Major wound infection | 1% (2/205) | ||
| Major gastrojejunostomy stenosis | 0.5% (1/205) | ||
| Major anastomic leak | 1.5% (3/205) | ||
| Major life threatening ketoacidosis | 0.5% (1/205) | ||
| Mortality | 0.5% (1/205) | ||
| Major nonfatal pulmonary embolism | 1% (2/205) | ||
| Pories (1995) | Perioperative | Mortality | 1.5% (9/608) |
| Early | Reoperation | 2.8% (17/608) | |
| Anastomotic stenosis | 3% (18/608)† | ||
| Minor wound infection | 8.7% (53/608) | ||
| Severe wound infection | 3% (18/608) | ||
| Splenic tears | 2.5% (15/608) | ||
| Minor wound seroma | 5.8% (35/608) | ||
| Subphrenic abscess | 2.5% (15/608) | ||
| Depression | 23.4% (142/608) | ||
| Bile reflux | 8.7% (53/608) | ||
| Gastritis | 13.2% (80/608) | ||
| Incisional hernia | 23.8% (145/608) | ||
| Cholethiasis | 11.3% (69/608) | ||
| Nutritional deficiency Vit B12 | 40% (243/608) | ||
| Nutritional deficiency anemia | 39% (237/608) | ||
| Staple line disruption | 15.1% (92/608) | ||
| Hospital readmission | 38.2% (232/608) | ||
| Dumping syndrome | 70.6% (429/608) | ||
| Mortality | 4.1% (25/608) |
*
Combined laparoscopic and open groups.
†
Calculated by ECRI.