Adverse Effects: Comparisons of Procedures. From ECRI (19).
| Comparison | Study (Year) |
Procedure | Timing of Event |
No. of Patients |
Description | Patients at Risk, % (n/N)* |
|---|---|---|---|---|---|---|
| AGB vs. VBG |
Morino (2003) |
AGB VBG |
Perioperative | 49 51 |
Conversion to open | 0% (0/49) 0% (0/51) |
| Mortality | 0% (0/49) 0% (0/51) |
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| Early | Any complications | 6% (3/39)^ 10% (5/51) |
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| Band slippage | 2% (1/49) 0% (0/51) |
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| Fistula at staple line | 0% (0/49) 2% (1/51) |
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| Port site hematoma | 2% (1/49) 0% (0/51) |
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| Port site infection | 2% (1/49) 0% (0/51) |
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| Prolonged pyrexia | 0% (0/49) 4% (2/51) |
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| Respiratory failure (not pulmonary embolism) | 0% (0/49)^ 4% (2/51) |
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| Late | Any complications | 33% (16/49)†^ 14% (7/50) |
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| 49 50 |
Asymptomatic pouch to fundus fistula | 0% (0/49) 2% (1/50) |
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| Band slippage | 18% (9/49)† | |||||
| Food intolerance | 2% (1/49) 0% (0/50) |
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| Gastric bezoar | 0% (0/49) 2% (1/50) |
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| Poor compliance | 2% (1/49) 0% (0/50) |
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| Port infection | 2% (1/49) 0% (0/50) |
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| Port twisted | 2% (1/49) 0% (0/50) |
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| Pouch dilation | 0% (0/49) 2% (1/50) |
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| Symptomatic reflux disease | 6% (3/49) 8% (4/50) |
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| Reoperation | 25% (12/49)† 0% (0/50) |
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| Nilsell (2001) |
AGB VBG |
Early | 29 30 |
Anastomotic leak | 0% (0/29) 3% (1/30 |
|
| Mortality | 0% (0/29) 0% (0/30) |
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| Late | Mortality | 3%(1/29) 3% (1/30) |
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| Staple line disruption | 0% (0/29)† 17% (5/30) |
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| Reoperation | 10% (3/2)† 37% (11/30) |
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| Ashy (1998) |
AGB VBG |
Early | 30 30 |
Any complications | 0% (0/30) 0% (0/30) |
|
| Mortality | 0% (0/30) 0% (0/30) |
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| Late | Any complications | 0% (0/30) | ||||
| 0% (0/30) | ||||||
| Mortality | 0% (0/30) 0% (0/30) |
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| VBG vs. RYGBP |
MacLean (1995) |
VBG RYGBP |
Perioperative | 54 52 |
Mortality | 0% (0/54) 0% (0/52) |
| Early | Abscess | 2% (1/54) 0% (0/52) |
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| Enlarged orifice | 13% (7/54)† 0% (0/52) |
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| Mortality | 0% (0/54) 0% (0/52) |
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| Staple line disruption | 4% (2/54)† 23% (12/52) |
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| Stenosis | 20% (11/54)† 0% (0/52) |
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| Stomal ulcer | 0% (0/54)† 13% (7/52) |
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| Late | Mortality | 0% (0/54) 0% (0/52) |
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| Reoperation | 43% (23/54)† 23% (12/52) |
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| Sugerman (1987) |
Early | 20 20 |
Mortality | 0% (0/20) 5% (1/20) |
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| Late | 16 18 |
Abnormal electrolytes | 0% (0/16) 0% (0/18) |
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| Abnormal liver function | 0% (0/16) 0% (0/18) |
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| Abnormal renal function | 0% (0/16) 0% (0/18) |
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| Conversion | 5% (1/20) 0% (0/20) |
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| Marginal ulcer | 0% (0/17) 6% (1/18) |
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| Mortality | 5% (1/20) 5% (1/20) | |||||
| Deficiency in albumin | 0% (0/17) 0% (0/18) |
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| Deficiency in folic acid | 0% (0/17) 0% (0/18) |
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| Deficiency in hemoglobin | 0% (0/17) 0% (0/18) |
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| Deficiency in magnesium | 0% (0/17) 0% (0/18) |
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| Deficiency in serum iron | 0% (0/17) 0% (0/18) |
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| Deficiency in calcium | 0% (0/17) 0% (0/18) |
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| Deficiency in transferrin | 0% (0/17) 0% (0/18) |
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| Deficiency in Vitamin B1 | 0% (0/17) 0% (0/18) |
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| Deficiency in Vitamin B12 | 18% (3/17) 39% (7/18) |
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| Deficiency in vitamin B6 | 0% (0/17) 0% (0/18) |
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| Deficiency in vitamin C | 0% (0/17) 0% (0/18) |
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| Deficiency in zinc | 0% (0/17) | |||||
| 0% (0/18) | ||||||
| Staple line disruption | 6% (1/17) 0% (0/18) |
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| Stomal erosion | 6% (1/17) 0% (0/18) |
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| Stomal stenosis | 0% (0/17)† 28% (5/18) |
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| RYBG vs. long-limb RYBG (LLRYGB) |
Feng (2003) |
RYGB LLRYGB |
Perioperative | 45 13 |
Any complications | 7% (3/45) 0% (0/13) |
| Leak at gastrojejunostomy |
2% (1/45) 0% (0/13) |
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| Wound infection | 4% (2/45) 0% (0/13) |
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| Choban (2002) |
RYGB LLRYGB |
Early | 35 34 |
Cirrhosis | 0% (0/35) 0% (0/34) |
|
| Leak and fistula | 3% (1/35) 0% (0/34) |
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| Mortality | 3% (1/35) 0% (0/34) |
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| Late | Mortality | 0% (0/35) 0% (0/34) |
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| Brolin | RYGB LLRYGB |
Perioperative | 22 23 |
Mortality | 0% (0/22) 0% (0/23) |
|
| Late | Mortality | 5% (1/22) 0% (0/23) |
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| Any | Vitamin B12 deficiency | 23% (5/22) 22% (5/23) |
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| Diarrhea | 0% (0/22) 0% (0/23) |
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| Folate deficiency | 14% (3/22) 13% (3/23) |
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| Hepatic dysfunction | 0% (0/22) 0% (0/23) |
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| Iron deficiency | 50% (11/22) 57% (13/23) |
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| Protein deficiency | 0% (0/22 0% (0/23) |
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| Vitamin/mineral deficiency | 73% (16/22) 74% (17/23) |
*
ECRI did all statistical analyses, except where noted by ^
†
Statistically significant.