Table 3: CARE H-F Results: NYHA Class and Quality of Life Scores*.
| Outcome | Medical Therapy Alone (N = 404) |
Medical Therapy and BiV Pacing (N = 409) |
Difference in Means | P |
|---|---|---|---|---|
| (95% CI) | ||||
| Mean (SD) at 90 days | Mean (SD) at 90 days | |||
| NYHA class | 2.7 (0.9) | 2.1 (1.0) | 0.6 | < .001 |
| (0.4–0.7) | ||||
| Minnesota Living with Heart | 40 (22) | 31 (22) | -10 | < .001 |
| Failure score† | (-8 to -12) | |||
| EuroQoL EQ-5D score‡ | 0.63 (0.29) | 0.70 (0.28) | 0.08 | < .001 |
| (0.04–0.12) |
†
Minnesota Living with Heart Failure scores range from 0 to 105; higher scores reflect poorer QoL.
‡
European Quality of Life–5 Dimensions scores range from -0.594 to 1.000; 1.000 indicates fully healthy; 0, dead
*
Cleland JGF, Daubert J, Erdmann E, Freemantle N, Gras D, Kappenberger L et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure (CARE-HF). New England Journal of Medicine 2005; 352:1539-1549; Copyright 2005 Massachusettes Medical Society. All rights reserved.(10)