Table 14: Overall GRADE and Strength of Recommendation.
| Quality | Estimated Prevalence in Ontario |
NNT* Death (Any Cause) |
Cost-Effectiveness | Cost in Ontario $ Millions (cdn) |
Overall Grade and Strength of Recommendation (Including Uncertainty) |
|
|---|---|---|---|---|---|---|
| BiV pacing* | Moderate/high | ~2,560 | 7 | $7,000–$59,000/QALY | 38–46 ~14–16/year over 4 years |
Moderate |
| BiV/ICD device* | Low Major study limitations |
~2,560 | 14 | ? Low quality data |
74–82 ~27–29/year over 4 years |
Weak |
*
BiV refers to biventricular; ICD, implantable cardioverter defibrillator; NNT, number needed to treat.