Table 2.
Biochemical and biomarker variables (mean ± SD) at induction (0), after 4-month BT (4), and after 6 months from induction (6)
| NSF (N = 62) |
SF (N = 12) |
|||||
|---|---|---|---|---|---|---|
| Month | 0 | 4 | 6 | 0 | 4 | 6 |
| HGB (g/dl) | 15.7 ± 0.9+Δ | 14.2 ± 0.9 | 14.2 ± 0.9 | 15.6 ± 0.5+Δ | 14.6 ± 0.8 | 13.9 ± 1.0 |
| Folic acid serum (ng/dl) | 6.1 ± 2.6+Δ | 3.9 ± 1.7 | 7.1 ± 2.5 | 7.1 ± 3.7+ | 3.8 ± 1.9 | 7.0 ± 2.4 |
| Calcium total (mg/dl) | 10.1 ± 0.4+Δ | 9.7 ± 0.4 | 9.8 ± 0.3* | 9.9 ± 0.3Δ | 9.6 ± 0.4 | 9.5 ± 0.2 |
| Iron (μg/dl) | 118.9 ± 51.4+ | 65.4 ± 24.1 | 130.4 ± 71.5* | 121.2 ± 53.8+ | 66.8 ± 22.6 | 71.7 ± 27.2 |
| Transferrin (mg/dl) | 303.9 ± 48.2 | 306.0 ± 28.5 | 307.6 ± 41.4 | 264.0 ± 53.5 | 302.4 ± 67.5 | 295.9 ± 50.4 |
| Ferritin (ng/ml) | 54.3 ± 30.0+Δ | 42.6 ± 22.5 | 22.8 ± 9.6 | 57.4 ± 30.2Δ | 38.7 ± 19.0 | 31.9 ± 16.5 |
| Transferrin saturation (%) | 39.1 ± 12.7+ | 21.4 ± 8.5 | 23.4 ± 9.2 | 41.1 ± 13.5+ | 22.1 ± 11.7 | 24.2 ± 10.8 |
| 25(OH)D (nmol/L) | 75.3 ± 16.3 | 64.6 ± 10.2 | 72.4 ± 13.8 | 70.5 ± 16.5 | 63.0 ± 12.4 | 66.4 ± 16.4 |
| PTH (ng/L) | 32.4 ± 14.9 | 50.2 ± 17.1 | 32.1 ± 19.9 | 31.9 ± 18.5 | 43.8 ± 17.8 | 37.4 ± 22.7 |
* p < 0.05 NSF vs. SF at the same examination date
+ p < 0.05 at the same group, between induction and end of BT
Δ p < 0.05 at the same group, between induction and 6-month